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thymic-dependent antigen

См. также в других словарях:

  • Central tolerance — is the mechanism by which newly developing T cells and B cells are rendered non reactive to self[1]. The concept of central tolerance was proposed in 1959 by Joshua Lederberg[2], as part of his general theory of immunity and tolerance, and is… …   Wikipedia

  • Chemorepulsion — is the directional movement of a cell away from a substance. Of the two directional varieties of chemotaxis, chemoattraction has been studied to a much greater extent. Only recently have the key components of the chemorepulsive pathway been… …   Wikipedia

  • Immunosenescence — refers to the gradual deterioration of the immune system brought on by natural age advancement. It involves both the host’s capacity to respond to infections and the development of long term immune memory, especially by vaccination [ cite… …   Wikipedia

  • Cell — The basic structural and functional unit in people and all living things. Each cell is a small container of chemicals and water wrapped in a membrane. Each cell in the human body there are 100 trillion cells in each of us contains the entire… …   Medical dictionary

  • Major histocompatibility complex — The major histocompatibility complex (MHC) is a large genomic region or gene family found in most vertebrates that encodes MHC molecules. MHC molecules play an important role in the immune system and autoimmunity. Proteins are continually… …   Wikipedia

  • Superantigen — [ thumb|Figure 1. Schematic of Superantigen stimulation compared to normal antigen presentation and activation [2] .] Superantigens (SAgs) are secreted proteins (exotoxins) that exhibit highly potent lymphocyte transforming (mitogenic) activity… …   Wikipedia

  • CD28 — is one of the molecules expressed on T cells that provide co stimulatory signals, which are required for T cell activation. CD28 is the receptor for B7.1 (CD80) and B7.2 (CD86). When activated by Toll like receptor ligands, the B7.1 expression is …   Wikipedia

  • CD90 — Thy 1 or CD90 (Cluster of Differentiation 90) is a 25–37 kDa heavily N glycosylated, glycophosphatidylinositol (GPI) anchored conserved cell surface protein with a single V like immunoglobulin domain, originally discovered as a thymocyte antigen …   Wikipedia

  • factor — 1. One of the contributing causes in any action. 2. One of the components that by multiplication makes up a number or expression. 3. SYN: gene. 4. A vitamin or other essential element. 5. An event, characteristic, or other definable entity that …   Medical dictionary

  • CD4 — For other uses, see CD 4 (disambiguation). CD4 molecule Crystallographic structure of the V set and C2 domains of human CD4.[1] …   Wikipedia

  • Regulatory T cell — Regulatory T cells (sometimes known as suppressor T cells) are a specialized subpopulation of T cells that act to suppress activation of the immune system and thereby maintain immune system homeostasis and tolerance to self antigens. The… …   Wikipedia

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